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PI Yasunori Yamamoto　Specially Appointed Professor

PI message

My main research topics including transmetalation between organometallic reagents and transition metals is a fundamental process involved in metal-catalyzed C-C bond-forming reactions. It is the first step in metal-catalyzed addition reaction and the second step in the metal-catalyzed cross-coupling reactions. In this field, I have developed novel cyclic triolborate salts which have high reactivity for transmetalation to transition metal complexes. Moreover, I recently developed a new catalytic cycle starting from transmetalation for the addition reaction of organoboronic acids and their enantioselective versions using chiral catalysts. These researches led to a development of bidentate bisphosphoramidite (Me-BIPAM) as a new chiral ligand which resulted in high enantioselectivities.

Research

Development of catalytic organic reactions or catalytic asymmetric reactions using organoboron compounds and C-H bond activation reaction

Member

• Yasunori Yamamoto

  Specially Appointed Professor

  Research Field

  Synthetic organic chemistry, Organometallic chemistry

Main Research Achievements

• T. Shirai, Y. Yamamoto, Angew. Chem. Int. Ed., 2015, 54, 9894−9897　
  DOI: 10.1002/anie.201504563
• T. Shirai, H. Ito, Y. Yamamoto, Angew. Chem. Int. Ed., 2014, 53, 2658−2661　
  DOI: 10.1002/anie.201400147
• Y. Yamamoto, K. Kurihara, N. Miyaura, Angew. Chem., Int. Ed., 2009, 48, 4414−4416　
  DOI: 10.1002/Anie.200901395
• Y. Yamamoto, M. Takizawa, X. Q. Yu, N. Miyaura, Angew. Chem. Int. Ed., 2008, 47, 928−931　DOI:10.1002/Anie.200704162
• T. Ohmura, Y. Yamamoto, N. Miyaura, J. Am. Chem. Soc., 2000, 122, 4990−4991　
  DOI: 10.1021/ja0002823

Contact

yasuyama(at)eng.hokudai.ac.jp